*Source: Symphony Health, an ICON plc Company, IDV®; July 2024 to September 2025.2

Early Symptom Relief and Endoscopic Control in UC1,3-5

Clinical response† as early as Week 4 and clinical remission,‡ endoscopic improvement,§ and endoscopic remission|| at Week 52, with long term data available up to ~3 years.

†Clinical response at Week 4 in UC per partial modified Mayo Score is a composite of Mayo stool frequency and rectal bleeding subscores and was defined as a decrease in total score ≥30% and ≥1 point from baseline and a decrease in rectal bleeding subscore ≥1 or rectal bleeding subscore of 0 or 11.

‡Clinical remission per modified Mayo score is defined as stool frequency subscore ≤1 and not greater than baseline, rectal bleeding subscore of 0, and endoscopic subscore ≤1 without friability.1

§Endoscopic improvement in UC is defined as Mayo endoscopic subscore of 0 or 1 without friability.1Endoscopic results are based on a full colonoscopy or flexible sigmoidoscopy, at the discretion of the investigator.6

||Endoscopic remission in UC is defined as an endoscopic subscore of 0.1 Endoscopic results are based on a full colonoscopy or flexible sigmoidoscopy, at the discretion of the investigator.6

SKYRIZI OBI

Get to know the OBI, a maintenance dosing device designed with your patients in mind.1

OBI
Over 95%

Formulary Coverage with SKYRIZI

With SKYRIZI, >95% of national commercial lives have formulary coverage under the medical and pharmacy benefit as of April 2026.7||

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About SKYRIZI

Learn about SKYRIZI's clinical experience in 4 indications and the first approved IL-23p19-specific MOA in Crohn's and UC.1

 Skyrizi Complete

Skyrizi Complete

Skyrizi Complete offers personalized support and potential savings for your patients. You can download the enrollment form for your patients to complete and submit while in your office.

||Coverage requirements and benefit designs vary by payer and may change over time. Please consult with payers directly for the most current reimbursement policies. 

IL-23=interleukin-23; IL-23p19=interleukin-23 subunit alpha; OBI=on-body injector.