Reliable 3-MONTH DOSING
2 PREFILLED SYRINGES PER DOSE,
ADMINISTERED BY SUBCUTANEOUS INJECTION AT:
Initiation
DOSE
WEEK 0
DOSE
WEEK 4
Month 3
DOSE
WEEK 16
Month 6
DOSE
WEEK 28
Month 9
DOSE
WEEK 40
Month 12
DOSE
WEEK 52
3-MONTH DOSING
after 2 initiation doses (150 mg/dose) at Weeks 0 and 4
2 administration options
for in-office use or self-administration after training
1 DOSAGE FOR ALL PATIENTS
regardless of weight, disease severity, or prior treatment
Dosing Considerations
SKYRIZI is intended for use under the guidance and supervision of a healthcare professional. Patients may self-inject SKYRIZI after training in subcutaneous injection technique. Instruct patients to inject 2 prefilled syringes for the full 150 mg/dose and to read the Instructions for Use before administration.1
Download dosing card

IMPORTANT SAFETY INFORMATION AND INDICATION FOR SKYRIZI™ (risankizumab-rzaa) 1
Indication
SKYRIZI is indicated for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.
Important Safety Information
Infection
SKYRIZI may increase the risk of infection. Do not initiate treatment with SKYRIZI in patients with a clinically important active infection until it resolves or is adequately treated.
In patients with a chronic infection or a history of recurrent infection, consider the risks and benefits prior to prescribing SKYRIZI. Instruct patients to seek medical advice if signs or symptoms of clinically important infection occur. If a patient develops such an infection or is not responding to standard therapy, closely monitor and discontinue SKYRIZI until the infection resolves.
Pre-Treatment Evaluation for Tuberculosis (TB)
Prior to initiating treatment with SKYRIZI, evaluate for TB infection and consider treatment in patients with latent or active TB for whom an adequate course of treatment cannot be confirmed. Monitor patients for signs and symptoms of active TB during and after SKYRIZI treatment. Do not administer SKYRIZI to patients with active TB.
Immunizations
Prior to initiating SKYRIZI, consider completion of all age appropriate immunizations according to current immunization guidelines.
Avoid use of live vaccines in patients treated with SKYRIZI.
Adverse Reactions
Most common (≥1 %) adverse reactions associated with SKYRIZI include upper respiratory infections, headache, fatigue, injection site reactions, and tinea infections.
Please see Full Prescribing Information.
US-SKZD-190350
REFERENCE
- SKYRIZI [package insert]. North Chicago, IL: AbbVie Inc.