Nothing more than 4 DOSES PER YEAR after initiation doses¹

Hi, it’s good to be here with you. I’m Kate. And you are one of the many people who have been prescribed SKYRIZI. After starting on SKYRIZI, there were two directions you could go: continue with in-office injections or inject at home.

You had a discussion with your doctor, and have decided to inject at home.

I’m going to show you how to do that...step by step, and address any questions you may have.

Still, there are probably a million things you’d rather be doing right now than learning about injecting your medicine. I get it. But this video will be helpful. So, stay with it. Because, well, there’s more to making SKYRIZI a part of your life than just learning how to inject.

When you sign up for Skyrizi Complete, you get a dedicated Nurse Ambassador.

They will get to know you and help you start and stay on track with your treatment plan.

So, let’s get started.

Leave SKYRIZI at room temperature for 15 to 30 minutes before injecting.

If you’re a little nervous, I totally get it. It may help you relax if you watch or listen to something that is soothing.

First, wash your hands. Then get the things you need, and settle into a place where you feel relaxed.

Now I’ll take you through the process step by step.

Make sure you have everything you need laid out:

2 alcohol swabs that are included in the package,

2 cotton balls, you can also use gauze pads,

your sharps container, which ensures your syringes are disposed of safely,

and of course, your 2 SKYRIZI prefilled syringes.

For one full dose, two injections are required.

We’re going to break the injection process down into 4 simple steps.

Let’s call them the 4 Ps.

Pick the injection site.

Prepare the syringe.

Pinch the skin.

And Push the plunger in.

There’s an “R” too for “Repeat.” Remember, one dose is two injections.

So, you will need to repeat the same injection steps for the second injection.

Pick the injection site—your left or right thigh or your stomach.

When you are using your second syringe, pick an injection site at least one inch away from the first site. Do not inject into the same site.

If you choose your lower stomach area, make sure you inject at least 2 inches away from your belly button.

Wipe the injection site in a circular motion with the alcohol swab (before both injections). Don’t inject through clothes, or into skin that doesn’t look normal.

Start with one syringe for the first injection. Now prepare the syringe.

Holding the syringe with the needle pointing down, check the liquid in the syringe.

It is normal to see one or more bubbles in the window.

The liquid should look clear to slightly yellow and may contain tiny white or clear particles.

DO NOT use if the liquid is cloudy or contains flakes or large particles.

To remove the needle cover, hold the syringe in one hand.

With the other hand, gently pull the needle cover straight off and throw it away.

You may see a drop of liquid at the end of the needle. This is normal.

DO NOT touch the needle with your fingers or let the needle touch anything.

For this demonstration, I’ll be using a practice pad.

Hold the body of the prefilled syringe in one hand between the thumb and index finger.

Gently pinch the area of cleaned skin with your other hand and hold it firmly.

Insert the needle into the skin at about a 45 degree angle using a quick, short movement. Hold the angle steady.

Slowly push the plunger all the way in until all of the liquid is injected and the syringe is empty.

Pull the needle out of the skin while keeping the syringe at the same angle. Release the plunger and allow the syringe to move up until the entire needle is covered by the needle guard.

The syringe needle guard will not activate unless all the liquid has been injected.

Press a cotton ball or gauze pad over the injection site and hold for 10 seconds.

DO NOT rub the injection site. You may have slight bleeding. This is normal.

Now that the syringe is empty, drop it into the sharps container.

Repeat these injection steps for the second syringe immediately following your first injection. Do not inject into the same site.

Be sure to pick a new site at least one inch away from your first injection.

In a nutshell here’s what you did.

You picked the injection site, prepared the syringe, pinched the skin, and pushed the plunger in. Then you did it again, using the second syringe.

Okay, so now you know how to inject.

After your starter doses at week 0 and week 4, SKYRIZI is dosed quarterly. That’s just 4 times a year or one dose for each season.

It’s important you don’t forget.

So, make sure you place reminders for ordering your medication and note your injection day on your calendar. You can also do this through the Skyrizi Complete App.

The Skyrizi Complete Sharps Disposal and Mail-back Service ensures your syringes are disposed of safely and in a socially responsible way.

There’s a bit to remember.

But you’ll get the hang of it. And you can always refer to this video or call us.

You’ve got this.